Wednesday, April 14, 2021

Can vaccinations stop the transmission of COVID?

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By Sarah Collins

HealthDay reporter

THURSDAY April 1, 2021 (HealthDay News) – This is the question everyone wants to answer because the reopening of the world depends on it: can coronavirus vaccines stop the transmission of the virus?

Today, 21 universities across the United States are teaming up to find out.

The project, called Prevent COVID U, was initiated by the COVID-19 Prevention Network hosted at the Fred Hutchinson Cancer Research Center in Seattle.

The study includes healthy students between the ages of 18 and 26 who are randomly assigned to immediate or subsequent vaccination groups. Both will receive hits from Moderna, with the latter group only receiving hits in July. The 12,000 participants will undergo daily nasal swab tests, provide periodic blood samples and identify close contacts, all to help researchers determine if the vaccine is preventing transmission.

“If you want to know if someone is capable of spreading the virus, you want to be able to do more than just detect the virus, don’t you?” explained Dr Kartik Cherabuddi. He is professor of epidemiology at the University of Florida and the school’s principal investigator on the study.

Continued

“If you’re infected, you can say, OK, there’s a virus being shed. But does that really mean it’s at a level that can be passed on to another person? And that’s where it is. once enrolled in the study, roommates, colleagues, classmates to also enroll with me, the people I spend the most time with. They are not followed as rigorously as the main study participant, but they have certain things that they would continue to record and record, “Cherabuddi said.

On Monday, President Joe Biden announced that 90% of all American adults would be eligible for vaccination by April 19 and that 200 million vaccines would be given in his first 100 days in office. Knowing this, students still sign up for the study even though there is a 50% chance that they will not be vaccinated for months – likely long after most of their friends and family have received. their doses.

Dr. Chris DeSouza is the head of the study branch at the University of Colorado. “So far we’ve had a great response from the students at UC Boulder,” he said. DeSouza is director of the school’s clinical and translational research center.

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CU Boulder Study Participants

“We have received many emails that we are working on to get them started. It was really nice to see because they are really interested in doing something to help. vaccine.’ That is, “We understand what the study is, and we would love to be involved and be part of the long term solution,” “added DeSouza.

Chase Willie, a senior at the Boulder campus, never quite knew how projects like this worked.

“I used to say to my dad, I always wondered who was in those studies, because you hear about it on the news,” Willie said. “I’ve always been like, ‘Who are they talking to?'”

So when Willie’s girlfriend emailed him about Prevent COVID U, he decided to submit a request. The media design manager then attended briefings about the study, and it was there that he learned that participating could mean waiting to be trapped later in the year. But, at that point, he felt like he was part of something important and decided to stay in the trial.

Continued

“The study sort of answers the big question the entire nation is currently asking about these vaccines,” he said. “Once you are vaccinated, can you still pass the virus on to other people? I think this is a question that came to my mind as well, and that I was really curious to find out. So even though I wasn’t immediately vaccinated, it would have been really cool to be part of a study that answers that. “

As it turned out, Willie had been assigned to the previous group and received his first Moderna shot last week.

Dr Amesh Adalja, a senior researcher at the Johns Hopkins Center for Health Security in Baltimore, said the study would benefit everyone.

“The main reason this is important is that it will have a real impact on how public health guidelines are published. [transmission] information from the US Centers for Disease Control and Prevention, data from health workers, as well as real data in places like Israel, where they have a highly vaccinated population, ”Adalja said.

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“We expect this study will in fact show that [vaccination] will likely have a positive result. But it’s important because [lack of transmission data] was something that caused the CDC to be cautious about activities that they believe are safe and not for people who have been vaccinated, ”he added.

More information

Visit the U.S. Centers for Disease Control and Prevention to learn more about Vaccines against covid-19.

SOURCES: Kartik Cherabuddi, MD, professor, epidemiology, University of Florida, and director, Antimicrobial Stewardship Program, UFHealth, Gainesville, Florida; Chris DeSouza, PhD, director, Center for Clinical and Translational Research, University of Colorado, Boulder; Amesh Adalja, MD, senior researcher, Johns Hopkins Center for Health Security, Baltimore; Chase Willie, student, University of Colorado, Boulder; University of Colorado, press release, March 29, 2021

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