Wednesday, May 21, 2025

Week 16 Saturday FanDuel Picks: Daily Fantasy Football Programming Tips For NFL DFS Tournaments

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There are so many opportunities to play NFL DFS in Week 16, so if you missed out on your fantasy football championship game, we’re here to help you still win. We’ve put together a FanDuel tournament lineup for Saturday’s three-game roster, which includes the Buccaneers at Lions, Cardinals at 49ers and Dolphins at Raiders.

The key to a small slate is not to sweat out the little overlaps that might bother you on a regular Sunday. An RB-WR stack from the same team doesn’t make much sense, but it could happen in a three-game contest. There is also less to choose from, so leaving money on the table isn’t the worst thing if you feel you’ve done better programming than just topping up the dollars.

Week 16 Saturday NFL DFS Lineup: FanDuel Tournament Pick

QB Kyler Murray, Cardinals vs. 49ers ($ 8,700)

If you just gave Murray his running stats without passing, he would be in the top 10 running backs this season. That’s how dominant he has been on the pitch, and when you pair that with supreme talent as a passer, he’ll always be a great game. On a short list, using Murray is even more obvious (with Tom Brady in second place against the Lions). It doesn’t look like any other quarter-quarterback on Saturday has Murray’s game-over-game advantage. When Murray played the Niners in Week 1 he had 27.3 FD points and the 49ers were much healthier than they are now.

SATURDAY DRAFTKINGS LINES: Bucs-Lions | 49ers-cardinals | Dolphins-Raiders

RB Leonard Fournette, Buccaneers @ Lions ($ 7,000)

Ronald Jones (COVID, finger) is unlikely to perform this week, which means this is the Fournette show against the NFL’s worst defense. Fournette has disappointed his fancy owners in the past, and FD is right on top of fair prices here, but he’s still tempting in this game. If he gets 15 runs and a few catches, he has the potential for a fantastic monster day.

FUEL RANGES ON SATURDAY: Bucs-Lions | 49ers-cardinals | Dolphins-Raiders

RB Jeff Wilson Jr., 49ers @ Cardinals ($ 6,000)

You’ll want to check on JWJ’s health before Saturday as he’s suffering from an ankle injury, but Raheem Mostert (ankle) is out so Wilson should lead that backfield if he’s healthy. Otherwise, pivot to Tevin Coleman and use those extra dollars elsewhere, but Wilson is a powerful runner who will get all the reach from the goal line and even catch a few assists. It looks a lot like Fournette for $ 1,000 less.

SATURDAY FULL SLATE DFS LINES: DraftKings

WR DeAndre Hopkins, Cardinals vs. 49ers ($ 8,700)

If you pay for Murray, you have to pay for Hopkins as well, especially on this short list. He may get the Richard Sherman treatment, but given Hopkins’ tendency to make incredible catches with a defender (or three) draped over him, we’re not too worried about that. Murray’s most obvious path to a great day is through Hopkins, so we want both.

WEEK 16 DFS CASH LINEUPS: DraftKings | FanDuel

WR Antonio Brown, Buccaneers @ Lions ($ 6,600)

In a three-game slate, you’re going to have an unconventional overlap, like a wide receiver and a running back on the same team. We’re playing Brown not in reaction to his 93-yard touchdown record in Week 15, but simply because he’s the cheapest of the three Tampa Bay wide receivers that negotiate production every week. The Lions can’t really keep any of them, so having shares in Mike Evans or Chris Godwin wouldn’t be a bad idea either.

LINES OF THE WEEK 16 DFS TOURNAMENT: DraftKings | FanDuel

WR Lynn Bowden Jr., Dolphins @ Raiders ($ 5,300)

Unless all three DeVante Parker (hamstrings), Jakeem Grant (hamstrings) and Mike Gesicki (shoulder) return, Bowden is expected to retain a leading role in the Miami attack as a slot catcher. . Tua Tagovailoa has targeted him 16 times in total over the past two weeks, so Bowden can rack up stats in a hurry if he’s on the pitch.

OVER WEEK 16 DFS: Best batteries | Best values | Programming creator

TE TJ Hockenson, Lions vs. Buccaneers ($ 6,200)

Overall, Tampa Bay has a solid defense. The only area the Buccaneers have struggled with is tight end defense as they are in the top 10 for fantasy points awarded for position. Hockenson is solidly priced compared to the top option on this slate, Darren Waller, and with our pick of Miami defense, it makes sense to go Hockenson here.

FLEX Salvon Ahmed, Dolphins @ Raiders ($ 6,600)

First, a note: if Myles Gaskin is activated from the COVID-19 / reserve list and is indeed active for the game, it is priced the same as Ahmed and should probably be your choice. Otherwise, Ahmed has just finished a 122-yard day and should regain some leeway against a Vegas defense that has given up the third-most FD points to running backs this season. (Update: Gaskin has been activated, and it makes sense as a logical pivot.)

DEF Miami Dolphins @ Raiders ($ 4,700)

It sounds simple, but the biggest advantage on a three-game roster probably comes from playing defense against players you don’t have in your lineup. We built the roster without any Raiders, and we have the salary to play the Dolphins, so that’s what we have. It helps that Miami have been an impressive defense throughout the season and will face either Marcus Mariota or a Derek Carr (groin) under 100%.



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